The best way to handle spam is to notify the sender that you no longer want to be included on their E-mail list and send a copy to the postmaster at the sender's site. Junk E-mail can be handled in much the same way as spam although you may have to specifically ask to be removed from their E-mail list. If you receive abusive E-mail, notify your system administrator and keep the E-mail message since it may be possible to trace the sender.
If the hoax messages become particularly annoying to you, there are Web and E-mail sites where you can report the sender (the United States IRS is always glad to hear about the "get rich quick" types since these people rarely report any income from these schemes). Many Internet sites now support an "abuse" account where you can report E-mail abuses. For example, if the hoax message came from a (mythical) site called we-are-nice-folks.com you could send an E-mail message to abuse@we-are-nice-folks.com and see if your E-mail message goes through.